Wednesday, October 17, 2007

Dianabol (methandrostenolone)


Dianabol (methandrostenolone)


Quick overview:


Active Life: 6-8 hours
Drug Class: Anabolic/Androgenic Steroid (Oral)
Average Dose: Men 15-50 mg/day......Women 5-10 mg/day
Acne: Yes, especially in higher dosages
Water Retention: Yes, similar to testosterone
High Blood Pressure: Yes
Liver Toxic: Yes
Aromatization: Yes
DHT Conversion: No
Decrease HPTA function: Yes, dose and cycle length dependant

Dianabol is the old Ciba brand name for the oral steroid methandrostenolone. It is a derivative of testosterone, exhibiting strong anabolic and moderate androgenic properties. This compound was first made available in 1960, and it quickly became the most favored and widely used anabolic steroid in all forms of athletics. This is likely due to the fact that it is both easy to use and extremely effective. In the U.S. Dianabol production had meteoric history, exploding for quite some time, then quickly dropping out of sight. Many were nervous in the late 80's when the last of the U.S. generics were removed from pharmacy shelves, the medical community finding no legitimate use for the drug anymore. But the fact that Dianabol has been off the U.S. market for over 10 years now has not cut its popularity. It remains the most commonly used black market oral steroid in the U.S. As long as there are countries manufacturing this steroid, it will probably remain so.

Similar to testosterone and Anadrol 50, Dianabol is a potent steroid, but also one which brings about noticeable side effects. For starters methandrostenolone is quite estrogenic. Gynecomastia is often a concern during treatment, and may present itself quite early into a cycle (particularly when higher doses are used). At the same time water retention can become a pronounced problem, causing a notable loss of muscle definition as both subcutaneous water and fat build. Sensitive individuals may therefore want to keep the estrogen under control with the addition of an anti-estrogen such as Nolvadex and/or Proviron. The stronger drugs Arimidex, Femara, or Aromasin (antiaromatase) would be a better choice if available.

In addition, androgenic side effects are common with this substance, and may include bouts of oily skin, acne and body/facial hair growth. Aggression may also be increased with a potent steroid such as this, so it would be wise not to let your disposition change for the worse during a cycle. With Dianabol there is also the possibility of aggravating a male pattern baldness condition. Sensitive individuals may therefore wish to avoid this drug and opt for a milder anabolic such as Deca-Durabolin. While Dianabol does convert to a more potent steroid via interaction with the 5-alpha reductase anzyme (the same enzyme responsible for converting testosterone to dihydrotestosterone), it has extremely little affinity to do so in the human body's. The androgenic metabolite 5alpha dihydromethandrostenolone is therefore produced only in trace amounts at best. Therefore the use of Proscar/Propecia would serve no real purpose.

Being moderately androgenic, Dianabol is really only a popular steroid with men. When used by women, strong virilization symptoms are of course a possible result. Some do however experiment with it, and find low doses (5mg) of this steroid extremely powerful for new muscle growth. Whenever taken, Dianabol will produce exceptional mass and strength gains. It's effectiveness is often compared to other strong steroids like testosterone and Anadrol 50, and it is likewise a popular choice for bulking purposes. A daily dosage of 20-40mg is enough to give almost anybody dramatic results. Some do venture much higher in dosage, but this practice usually leads to a more profound incidence of side effects. It additionally combines well with a number of other steroids. It is noted to mix particularly well with the mild anabolic Deca-Durabolin. Together one can expect an exceptional muscle and strength gains, with side effects not much worse than one would expect from Dianabol alone. For all out mass, a long acting testosterone ester like enanthate can be used. With the similarly high estrogenic/androgenic properties of this androgen, side effects may be extreme with such a combination however. Gains would be great as well, which usually makes such an endeavor worthwhile to the user. As discussed earlier, ancillary drugs can be added to reduce the side effects associated with this kind of cycle.

In order to withstand oral administration, this compound is c17 alpha alkylated. We know that this alteration protects the drug from being deactivation by the liver (allowing nearly all of the drug entry into the bloodstream), however it can also be toxic to this organ. Prolonged exposure to c17 alpha alkylated substances can result in actual damage, possibly even the development of certain kinds of cancer. To be safe one might want to visit the doctor a couple of times during each cycle to keep an eye on their liver enzyme values. Cycles should also be kept short, usually less than 8 weeks long to avoid doing any noticeable damage. Jaundice (bile duct obstruction) is usually the first visible sign of liver trouble, and should be looked out for. This condition produces an unusual yellowing of the skin, as the body has trouble processing bilirubin. In addition to the skin, the whites of the eyes may also yellow, a clear indicator of trouble. Should this occur the drug should be discontinued immediately and a doctor visited. This is usually a point where further, permanent damage can be avoided.

It is also interesting to note that methandrostenolone is structurally identical to boldenone (EQ), except that it contains the added c17 alpha alkyl group discussed above. This fact makes clear the impact of altering a steroid in such a way, as these two compounds appear to act very differently in the body. The main dissimilarity seems to lie in the tendency for estrogenic side effects, which seems to be much more pronounced with Dianabol. Equipoise is known to be quite mild in this way, and users therefore commonly take this drug without any need of an anti-estrogen. Dianabol is much more estrogenic not because it is more easily aromatized, as in fact the 17 alpha methyl group and c1-2 double bond both slow the process of aromatization. The problem is that methandrostenolone converts to l7alpha methylestradiol, a more biologically active form of estrogen than regular estradiol. But Dianabol also appears to be much more potent in terms of muscle mass compared to boldenone, supporting the notion that estrogen does play an important role in anabolism. In fact boldenone and methandrostenolone differ so much in their potencies as anabolics that the two are rarely though of as related. As a result, the use of Dianabol is typically restricted to bulking phases of training while Equipoise is considered an excellent cutting or lean-mass building steroid.

The half-life of Dianabol is only about 3 to 4 hours, a relatively short time. This means that a single daily dosage schedule will produce a varying blood level, with ups and downs throughout the day. The user likewise has a choice, to either split up the tablets during the day or to take them all at one time. The usual recommendation has been to divide them and try to regulate the concentration in your blood. This however, will produce a lower peak blood level than if the tablets were taken all at once, so there may be a trade off with this option. The steroid researcher Bill Roberts also points out that a single-episode dosing schedule should have a less dramatic impact on the hypothalamic-pituitary-testicular axis, as there is a sufficient period each day where steroid hormone levels are not extremely exaggerated. I tend to doubt hormonal stability can be maintained during such a cycle however, but do notice that anecdotal evidence often still supports single daily doses to be better for overall results. Perhaps this is the better option. Since we know the blood concentration will peak about 1.5 to 3 hours after administration, we may further wonder the best time to take our tablets. It seems logical that taking the pills earlier in the day, preferably some time before training, would be optimal. This would allow a considerable number of daytime hours for an androgen rich metabolism to heighten the uptake of nutrients, especially the critical hours following training.

Monday, October 15, 2007

Oxandrolone (Oxandrin) - ANAVAR

Oxandrolone (Oxandrin) is an anabolic steroid created by Searle Laboratories under the trademark Anavar, and introduced into the US in 1964. It is taken orally, and unlike other steroids delivered in this manner, most of which are Class II steroids, the majority of its effects are due to reaction with the androgen receptor. In sufficient dosage, Oxandrolone is highly likely to bind well with the receptor, and is therefore a Class I steroid, while having few other side-effects. The drug was prescribed for a number of medical disorders causing involuntary weight loss, in order to promote muscle regrowth. It had also been shown to be partially successful in treating cases of osteoporosis. However, in part due to bad publicity from its illegal use by bodybuilders, Oxandrolone was discontinued by Searle Laboratories in 1989. It was picked up by Bio-Technology General Corporation who, following successful clinical trials in 1995, released it under the tradename Oxandrin. It was approved for orphan drug status by the Food and Drug Administration (FDA) in treating alcoholic hepatitis, Turner's syndrome, and weight loss caused by HIV. In addition, the drug has shown positive results in treating anaemia and hereditary angioedema. Clinical studies however have shown links between prolonged use of the drug and problems of liver toxicity similar to those found with other 17α-alkylated steroids. Even in small dosages, many users reported gastro-intestinal problems such as bloating, nausea, and diarrhoea. Before the Controlled Substances Act was passed to restrict the production, sale, and usage of anabolic steroids, Oxandrolone's characteristics lent itself well towards use by female athletes. Its specificity targeting the androgen receptor meant that, unlike many other steroids, it had not been reported to cause stunted growth in younger users, and at typical dosage rarely caused noticeable masculinising effects outside of stimulating muscle growth. In addition, Oxandrolone does not aromatise at any dosage, and is not easily metabolised into DHT or oestrogen. As such, a typical dose of 20-30 mg provided elevated androgen levels for up to eight hours. To increase effectiveness, bodybuilders typically "stacked" the drug with others such as Testosterone, further enhancing body mass gain.

Wednesday, October 10, 2007

Testosterone cypionate

Testosterone cypionate


Quick overview:


Active Life: 15-16 days
Drug Class: Anabolic/Androgenic Steroid (for injection)
Average Dose: Men 250-1000 mg/week
Acne: Yes
Testosterone cypionate
Water Retention: Yes, high
High Blood Pressure: Yes
Liver Toxic: Low, except in mega dosages
Aromatization:Yes, high
DHT Conversion: Yes, high
Decrease HPTA function: Yes, severe


American athletes have a long and fond relationship with Testosterone cypionate. While Testosterone enanthate is manufactured widely throughout the world, cypionate seems to be almost exclusively an American item. It is therefore not surprising that American athletes particularly favor this testosterone ester. But many claim this is not just a matter of simple pride, often swearing cypionate to be a superior product, providing a bit more of a "kick" than enanthate. At the same time it is said to produce a slightly higher level of water retention, but not enough for it to be easily discerned. Of course when we look at the situation objectively, we see these two steroids are really interchangeable, and cypionate is not at all superior. Both are long acting oil-based injectables, which will keep testosterone levels sufficiently elevated for approximately two weeks. Enanthate may be slightly better in terms of testosterone release, as this ester is one carbon atom lighter than cypionate (remember the ester is calculated in the steroids total milligram weight). The difference is so insignificant however that no one can rightly claim it to be noticeable (we are maybe talking a few milligrams per shot). Regardless, cypionate came to be the most popular testosterone ester on the U.S. black market for a very long time

As with all testosterone injectables, one can expect a considerable gain in muscle mass and strength during a cycle. Since testosterone readliy converts to estrogen, the mass gained from this drug is likely to be accompanied by quite a bit of water retention. The resulting loss of definition of course makes cypionate a very poor choice for dieting or cutting phases. The excess level of estrogen brought about by this drug can also cause one to develop gynecomastia rather quickly. Should one notice an uncomfortable soreness, swelling or lump under the nipple, an ancillary drug like Nolvadex should be added immediately. This will minimize the effect of estrogen greatly, making the steroid much more tolerable to use. The powerful anti-aromatases Arimidex, Femara, or Aromasin are yet a better choice. Those who have a known sensitivity to estrogen may find it more beneficial to use ancillary drugs like Nolvadex and Proviron from the onset of the cycle, in order to prevent estrogen related side effects before they become apparent.

Since testosterone is the primary male androgen, we should also expect to see pronounced androgenic side effects with this drug. Much intensity is related to the rate in which the body converts testosterone into dihydrotestosterone (DHT). This, as you know, is the devious metabolite responsible for the high prominence of androgenic side effects associated with testosterone use. This includes the development of oily skin, acne, body/facial hair growth and male pattern balding. Those worried that they may have a genetic predisposition toward male pattern baldness may wish to avoid testosterone altogether. Others opt to add the ancillary drug Proscar/Propecia, that prevents the conversion of testosterone to dihydrotestosterone. This can greatly reduce the chance for running into a hair loss problem, and will probably lower the intensity of other androgenic side effects. Although active in the body for much longer time, cypionate is injected on a weekly or bi-weekly basis in order to maintain stable blood levels. At a dosage of 250mg to 800mg per week we should certainly see dramatic results. It is interesting to note that while a large number of other steroidal compounds have been made available since testosterone injectables, they are still considered to be the dominant bulking agents among bodybuilders. There is little argument that these are among the most powerful mass drugs. When taking dosages above 800-1000mg per week there is little doubt that water retention will come to be the primary gain, far outweighing the new mass accumulation. The practice of "megadosing" is therefore inefficient, especially when we take into account the typical high cost of steroids today.

It is also important to remember that the use of an injectable testosterone will quickly suppress endogenous testosterone production. It is therefore mandatory to complete a proper post cycle therapy, constisting of HCG and Clomid or Nolvadex at the conclusion of a cycle. This should help the user avoid a strong "crash" due to hormonal imbalance, which can strip away much of the new muscle mass and strength. This is no doubt the reason why many athletes claim to be very disappointed with the final result of steroid use, as there is often only a slight permanent gain if anabolics are discontinued incorrectly. Of course we cannot expect to retain every pound of new bodyweight after a cycle. This is especially true whenever we are withdrawing a strong (aromatizing) androgen like testosterone, as a considerable drop in weight (and strength) is to be expected as retained water is excreted. This should not be of much concern; instead the user should focus on ancillary drug therapy so as to preserve the solid mass underneath. Another way athletes have found to lessen the "crash", is to first replace the testosterone with a milder anabolic like Deca-Durabolin. This steroid is administered alone, at a typical dosage (200-400mg per week), for the following month or two. In this "stepping down" procedure the user is attempting to turn the watery bulk of a strong testosterone into the more solid muscularity we see with nandrolone preparations. In many instances this practice proves to be very effective. Of course we must remember to still administer ancillary drugs at the conclusion, as endogenous testosterone production will not be rebounding during the Deca therapy.

Tuesday, October 9, 2007

Testosterone cypionate

Testosterone cypionate


Quick overview:


Active Life: 15-16 days
Drug Class: Anabolic/Androgenic Steroid (for injection)
Average Dose: Men 250-1000 mg/week
Acne: Yes
Testosterone cypionate
Water Retention: Yes, high
High Blood Pressure: Yes
Liver Toxic: Low, except in mega dosages
Aromatization:Yes, high
DHT Conversion: Yes, high
Decrease HPTA function: Yes, severe


American athletes have a long and fond relationship with Testosterone cypionate. While Testosterone enanthate is manufactured widely throughout the world, cypionate seems to be almost exclusively an American item. It is therefore not surprising that American athletes particularly favor this testosterone ester. But many claim this is not just a matter of simple pride, often swearing cypionate to be a superior product, providing a bit more of a "kick" than enanthate. At the same time it is said to produce a slightly higher level of water retention, but not enough for it to be easily discerned. Of course when we look at the situation objectively, we see these two steroids are really interchangeable, and cypionate is not at all superior. Both are long acting oil-based injectables, which will keep testosterone levels sufficiently elevated for approximately two weeks. Enanthate may be slightly better in terms of testosterone release, as this ester is one carbon atom lighter than cypionate (remember the ester is calculated in the steroids total milligram weight). The difference is so insignificant however that no one can rightly claim it to be noticeable (we are maybe talking a few milligrams per shot). Regardless, cypionate came to be the most popular testosterone ester on the U.S. black market for a very long time

As with all testosterone injectables, one can expect a considerable gain in muscle mass and strength during a cycle. Since testosterone readliy converts to estrogen, the mass gained from this drug is likely to be accompanied by quite a bit of water retention. The resulting loss of definition of course makes cypionate a very poor choice for dieting or cutting phases. The excess level of estrogen brought about by this drug can also cause one to develop gynecomastia rather quickly. Should one notice an uncomfortable soreness, swelling or lump under the nipple, an ancillary drug like Nolvadex should be added immediately. This will minimize the effect of estrogen greatly, making the steroid much more tolerable to use. The powerful anti-aromatases Arimidex, Femara, or Aromasin are yet a better choice. Those who have a known sensitivity to estrogen may find it more beneficial to use ancillary drugs like Nolvadex and Proviron from the onset of the cycle, in order to prevent estrogen related side effects before they become apparent.

Since testosterone is the primary male androgen, we should also expect to see pronounced androgenic side effects with this drug. Much intensity is related to the rate in which the body converts testosterone into dihydrotestosterone (DHT). This, as you know, is the devious metabolite responsible for the high prominence of androgenic side effects associated with testosterone use. This includes the development of oily skin, acne, body/facial hair growth and male pattern balding. Those worried that they may have a genetic predisposition toward male pattern baldness may wish to avoid testosterone altogether. Others opt to add the ancillary drug Proscar/Propecia, that prevents the conversion of testosterone to dihydrotestosterone. This can greatly reduce the chance for running into a hair loss problem, and will probably lower the intensity of other androgenic side effects. Although active in the body for much longer time, cypionate is injected on a weekly or bi-weekly basis in order to maintain stable blood levels. At a dosage of 250mg to 800mg per week we should certainly see dramatic results. It is interesting to note that while a large number of other steroidal compounds have been made available since testosterone injectables, they are still considered to be the dominant bulking agents among bodybuilders. There is little argument that these are among the most powerful mass drugs. When taking dosages above 800-1000mg per week there is little doubt that water retention will come to be the primary gain, far outweighing the new mass accumulation. The practice of "megadosing" is therefore inefficient, especially when we take into account the typical high cost of steroids today.

It is also important to remember that the use of an injectable testosterone will quickly suppress endogenous testosterone production. It is therefore mandatory to complete a proper post cycle therapy, constisting of HCG and Clomid or Nolvadex at the conclusion of a cycle. This should help the user avoid a strong "crash" due to hormonal imbalance, which can strip away much of the new muscle mass and strength. This is no doubt the reason why many athletes claim to be very disappointed with the final result of steroid use, as there is often only a slight permanent gain if anabolics are discontinued incorrectly. Of course we cannot expect to retain every pound of new bodyweight after a cycle. This is especially true whenever we are withdrawing a strong (aromatizing) androgen like testosterone, as a considerable drop in weight (and strength) is to be expected as retained water is excreted. This should not be of much concern; instead the user should focus on ancillary drug therapy so as to preserve the solid mass underneath. Another way athletes have found to lessen the "crash", is to first replace the testosterone with a milder anabolic like Deca-Durabolin. This steroid is administered alone, at a typical dosage (200-400mg per week), for the following month or two. In this "stepping down" procedure the user is attempting to turn the watery bulk of a strong testosterone into the more solid muscularity we see with nandrolone preparations. In many instances this practice proves to be very effective. Of course we must remember to still administer ancillary drugs at the conclusion, as endogenous testosterone production will not be rebounding during the Deca therapy.

Saturday, October 6, 2007

Testosterone cypionate

Testosterone cypionate


Quick overview:


Active Life: 15-16 days
Drug Class: Anabolic/Androgenic Steroid (for injection)
Average Dose: Men 250-1000 mg/week
Acne: Yes
Testosterone cypionate
Water Retention: Yes, high
High Blood Pressure: Yes
Liver Toxic: Low, except in mega dosages
Aromatization:Yes, high
DHT Conversion: Yes, high
Decrease HPTA function: Yes, severe


American athletes have a long and fond relationship with Testosterone cypionate. While Testosterone enanthate is manufactured widely throughout the world, cypionate seems to be almost exclusively an American item. It is therefore not surprising that American athletes particularly favor this testosterone ester. But many claim this is not just a matter of simple pride, often swearing cypionate to be a superior product, providing a bit more of a "kick" than enanthate. At the same time it is said to produce a slightly higher level of water retention, but not enough for it to be easily discerned. Of course when we look at the situation objectively, we see these two steroids are really interchangeable, and cypionate is not at all superior. Both are long acting oil-based injectables, which will keep testosterone levels sufficiently elevated for approximately two weeks. Enanthate may be slightly better in terms of testosterone release, as this ester is one carbon atom lighter than cypionate (remember the ester is calculated in the steroids total milligram weight). The difference is so insignificant however that no one can rightly claim it to be noticeable (we are maybe talking a few milligrams per shot). Regardless, cypionate came to be the most popular testosterone ester on the U.S. black market for a very long time

As with all testosterone injectables, one can expect a considerable gain in muscle mass and strength during a cycle. Since testosterone readliy converts to estrogen, the mass gained from this drug is likely to be accompanied by quite a bit of water retention. The resulting loss of definition of course makes cypionate a very poor choice for dieting or cutting phases. The excess level of estrogen brought about by this drug can also cause one to develop gynecomastia rather quickly. Should one notice an uncomfortable soreness, swelling or lump under the nipple, an ancillary drug like Nolvadex should be added immediately. This will minimize the effect of estrogen greatly, making the steroid much more tolerable to use. The powerful anti-aromatases Arimidex, Femara, or Aromasin are yet a better choice. Those who have a known sensitivity to estrogen may find it more beneficial to use ancillary drugs like Nolvadex and Proviron from the onset of the cycle, in order to prevent estrogen related side effects before they become apparent.

Since testosterone is the primary male androgen, we should also expect to see pronounced androgenic side effects with this drug. Much intensity is related to the rate in which the body converts testosterone into dihydrotestosterone (DHT). This, as you know, is the devious metabolite responsible for the high prominence of androgenic side effects associated with testosterone use. This includes the development of oily skin, acne, body/facial hair growth and male pattern balding. Those worried that they may have a genetic predisposition toward male pattern baldness may wish to avoid testosterone altogether. Others opt to add the ancillary drug Proscar/Propecia, that prevents the conversion of testosterone to dihydrotestosterone. This can greatly reduce the chance for running into a hair loss problem, and will probably lower the intensity of other androgenic side effects. Although active in the body for much longer time, cypionate is injected on a weekly or bi-weekly basis in order to maintain stable blood levels. At a dosage of 250mg to 800mg per week we should certainly see dramatic results. It is interesting to note that while a large number of other steroidal compounds have been made available since testosterone injectables, they are still considered to be the dominant bulking agents among bodybuilders. There is little argument that these are among the most powerful mass drugs. When taking dosages above 800-1000mg per week there is little doubt that water retention will come to be the primary gain, far outweighing the new mass accumulation. The practice of "megadosing" is therefore inefficient, especially when we take into account the typical high cost of steroids today.

It is also important to remember that the use of an injectable testosterone will quickly suppress endogenous testosterone production. It is therefore mandatory to complete a proper post cycle therapy, constisting of HCG and Clomid or Nolvadex at the conclusion of a cycle. This should help the user avoid a strong "crash" due to hormonal imbalance, which can strip away much of the new muscle mass and strength. This is no doubt the reason why many athletes claim to be very disappointed with the final result of steroid use, as there is often only a slight permanent gain if anabolics are discontinued incorrectly. Of course we cannot expect to retain every pound of new bodyweight after a cycle. This is especially true whenever we are withdrawing a strong (aromatizing) androgen like testosterone, as a considerable drop in weight (and strength) is to be expected as retained water is excreted. This should not be of much concern; instead the user should focus on ancillary drug therapy so as to preserve the solid mass underneath. Another way athletes have found to lessen the "crash", is to first replace the testosterone with a milder anabolic like Deca-Durabolin. This steroid is administered alone, at a typical dosage (200-400mg per week), for the following month or two. In this "stepping down" procedure the user is attempting to turn the watery bulk of a strong testosterone into the more solid muscularity we see with nandrolone preparations. In many instances this practice proves to be very effective. Of course we must remember to still administer ancillary drugs at the conclusion, as endogenous testosterone production will not be rebounding during the Deca therapy.

Thursday, October 4, 2007

THG Steroids by Balco

THG Steroids by Balco



Known as a “designer” steroid, THG’s complete name is tetrahydrogestrinone, and is used by athletes to enhance their performance.
The United States Food and Drug Administration issued a statement on October 28, 2003 that THG is a new unapproved drug.
It therefore cannot be marketed without the FDA’s approval because it poses some health risks to consumers, and (not surprisingly) is working with other agencies to aggressively enforce this prohibition. While manufacturers would most likely introduce THG as a dietary supplement, the FDA believes that it does not meet the official definition of what a dietary supplement is.
THG, according to the FDA, is associated with two other synthetic anabolic steroids: gestrinone and trenbolone and they are taken by athletes who want to build muscle mass. THG was reported to the FDA by the US Anti-Doping Agency.

THG Steroid News
In 2003, four US Track and Field athletes and at least one famous European sprinter were discovered to have used THG. A scandal erupted involving the use of THG; and suggests that it was manipulated by chemists so that it becomes undetectable during doping tests. The scandal apparently began when an athletics coach anonymously contacted the US Anti-Doping Agency reporting that top athletes have been using THG. He then submitted a syringe containing THG to the doping agency, and they proceeded to analyze the components.
The reason athletes use THG is to deliver a top notch performance during competition and to have a boost of strength during competition. THG is also used to enable tired athletes recover quickly from the rigorous training. If the name “Balco” ever comes up in steroid conversation, it was identified by the FDA as the source of THG.

THG: Friend or Foe?
Opinion is divided about the use of enhancers by athletes. Professional sports can be a taxing occupation, and fatigue is the number one enemy of athletic competition. There are therefore groups of individuals who would support the use of THG while others espouse zero tolerance for any type of drug or supplement in professional competition.
Even if the use of steroids is pervasive in sports today, efforts continue to prevent athletes from using it. As a result of the scandal, the World Anti-Doping Agency (WADA) has transmitted testing methods for THG to all laboratories involved with the International Olympic Committee.
The test for THG detection was developed by the University of California in Los Angeles, and is now officially going to be used as part of the regular blood doping screening process conducted by laboratories.

THG Steroid Dangers
THG, like other anabolic steroids, is potentially very dangerous. It can cause damage to the liver, cause heart disease and trigger rage and anxiety. Although not enough scientific evidence can prove it, doctors believe that THG, because of its components, can also cause hair growth in women, and baldness and infertility in men.
Since the scandal broke out, more sports will be employing THG testing. These include horseracing (where urine samples of thoroughbreds will be tested for THG), the International Ski Federation, the NCAA, and others.

Wednesday, October 3, 2007

Oxandrolone (Oxandrin) - ANAVAR

Oxandrolone (Oxandrin) is an anabolic steroid created by Searle Laboratories under the trademark Anavar, and introduced into the US in 1964. It is taken orally, and unlike other steroids delivered in this manner, most of which are Class II steroids, the majority of its effects are due to reaction with the androgen receptor. In sufficient dosage, Oxandrolone is highly likely to bind well with the receptor, and is therefore a Class I steroid, while having few other side-effects. The drug was prescribed for a number of medical disorders causing involuntary weight loss, in order to promote muscle regrowth. It had also been shown to be partially successful in treating cases of osteoporosis. However, in part due to bad publicity from its illegal use by bodybuilders, Oxandrolone was discontinued by Searle Laboratories in 1989. It was picked up by Bio-Technology General Corporation who, following successful clinical trials in 1995, released it under the tradename Oxandrin. It was approved for orphan drug status by the Food and Drug Administration (FDA) in treating alcoholic hepatitis, Turner's syndrome, and weight loss caused by HIV. In addition, the drug has shown positive results in treating anaemia and hereditary angioedema. Clinical studies however have shown links between prolonged use of the drug and problems of liver toxicity similar to those found with other 17α-alkylated steroids. Even in small dosages, many users reported gastro-intestinal problems such as bloating, nausea, and diarrhoea. Before the Controlled Substances Act was passed to restrict the production, sale, and usage of anabolic steroids, Oxandrolone's characteristics lent itself well towards use by female athletes. Its specificity targeting the androgen receptor meant that, unlike many other steroids, it had not been reported to cause stunted growth in younger users, and at typical dosage rarely caused noticeable masculinising effects outside of stimulating muscle growth. In addition, Oxandrolone does not aromatise at any dosage, and is not easily metabolised into DHT or oestrogen. As such, a typical dose of 20-30 mg provided elevated androgen levels for up to eight hours. To increase effectiveness, bodybuilders typically "stacked" the drug with others such as Testosterone, further enhancing body mass gain.